Retinal stem cell therapies: from laboratory models to clinical trials
Image: B-scan of the retina showing the various layers of retina and choroid by Firoz, M.; Shome, N.; Wong, N.; Jonnalagadda, P.; Tunga, H.; Shafiee, A.; Shafiee, A.; Bobba, S.;
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Oxford, United Kingdom
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Perspectives from the leading edge
Notes, commentary and analysis on retinal disease, gene and cell therapy and the business of bringing new treatments to patients.
A place for Professor Fischer’s thinking on the developments shaping the field, written for the people making decisions in it. Clinical developments, trial readouts, regulatory shifts and the commercial questions that follow.
In vivo gene editing for inherited retinal disease: moving towards the clinic
Image: B-scan of the retina showing the various layers of retina and choroid by Firoz, M.; Shome, N.; Wong, N.; Jonnalagadda, P.; Tunga, H.; Shafiee, A.; Shafiee, A.; Bobba, S.;
Artificial intelligence in inherited retinal dystrophies: promise, and what stands in the way
AI models can already predict disease-causing variants, separate phenotypically similar dystrophies and segment retinal layers. A review asks why so little of it has reached routine practice, and what would have to change.
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